EGCG抗肿瘤作用与STAT3信号通路的研究进展

Journal of Modern Medicine & Health(2013)

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Abstract
<正>表没食子儿茶素没食子酸酯(epigallocatechin-3-gallate,EGCG)是绿茶提取物茶多酚的主要活性成分,约占儿茶素总量的80%。大量研究发现其具有抗癌、抗心血管疾病、抗自由基损害等生物学作用,但具体作用机制仍不清楚。信号传导与转录激活子3(signal transducer and activator of transcription 3,STAT3)是一种存在于细胞质被磷酸化后进入细胞核调节特定基因表达的蛋白质,
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