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SARI基因的结构与功能

周人杰,肖颖彬

Chinese Journal of Clinicians(Electronic Edition)（2012）

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Abstract
<正>SARI(suppressor of AP-1and regulated by interferon)是在2008年通过差减杂交(subtraction hybridization)技术发现的一种新的抑癌基因[1],是一种新型的含碱性亮氨酸拉链的Ⅰ型干扰素诱导的早期反应基因,从结构特性而言,与激活转录因子(ac-tivating transcription factor,ATF)具有相似之处,故又称BATF2(basic leucine zipper transcription factor,ATF-like2),
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