MicroRNA-21通过抑制PTEN减少人脐静脉内皮细胞缺氧后的凋亡
Chinese Journal of Pathophysiology（2012）
Abstract
<正>目的:探讨microRNA-21(miR-21)在人脐静脉内皮细胞(HUVECs)缺氧损伤中的作用及调控机制。方法:荧光定量PCR检测HUVECs缺氧16和24 h后miR-21的表达模式。通过转染miR-21 mimic和inhibitor建立其过表达和沉默体系,
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