复发性鼻息肉中VEGF和COX-2的表达与相关性研究
Beijing Medical Journal（2012）
Abstract
<正>鼻息肉是耳鼻咽喉科常见病、多发病,以极厚水肿的鼻黏膜在鼻腔或鼻窦内形成单发或多发息肉为临床特征。近年来国内外研究证实环氧化酶2(cyclooxygcnase-2,COX-2)作为一种炎症介质[1],与鼻息肉发病密切相关;血管内皮生长因子(vascularen-dothelial growth factor,VEGF)具有很强的促进血管内皮细胞分裂增生能力,能增强毛细血管通透性而促进血管新生,在创伤修复、肿瘤形成、慢性炎症的
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