Abstract 14575: Angiotensin Ii-and High Fat Diet-Accelerated Atherosclerosis is Attenuated in Skp2-Deficient Mice

Timo Johannssen,Arnd Heuser,Joerg Drenckhahn,Yasunori Takata,Kai Kappert,Mattias Roser, Dietlind Zohlnhöfer,Wilhelm Haverkamp,Ludwig Thierfelder,Florian Blaschke

Circulation（2012）

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摘要

Atherosclerosis is a chronic inflammatory disease in which macrophages play a major role in all stages of development. S-phase kinase-associated protein 2 (Skp2) is a central component of the E3 ub...

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atherosclerosis,angiotensin,ii-and,diet-accelerated

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