宫颈癌遗传易感性研究进展

Maternal and Child Health Care of China（2012）

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Abstract

<正>宫颈癌(cervical cancer,CC)是女性生殖系统最常见的恶性肿瘤。流行病学显示,99%的患者感染高危型人乳头瘤病毒(human papillomavirus,HPV),HPV是宫颈癌的首要病因。然而,临床上约80%的女性一生中曾有HPV感染,只有5%～10%的高危HPV持续感染者进展为宫颈癌,其中的内在原因一直备受关注。研究表明,高危人群罹患宫颈癌的风险

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