血管紧张素Ⅰ转化酶基因多态性与2型糖尿病肾脏疾病的关系

Chinese Remedies & Clinics(2012)

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Abstract
<正>糖尿病肾脏疾病(diabetic kidney disease,DKD)是2型糖尿病(T2DM)重要的微血管并发症,在T2DM中约5%的患者在被诊断为糖尿病的同时就已存在糖尿病的肾脏损害。研究发现DKD的发生与血流动力学异常[1]有关,血管紧张素(AT)-Ⅱ是机体内一种强烈的缩血管物质,对血管调节具有
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