谷氨酰内切酶的催化特性研究与应用进展

Journal of Jiangsu University(Medicine Edition)(2012)

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Abstract
<正>谷氨酰内切酶(glutamyl endoproteinase,EC3.4.21.19)属于丝氨酸蛋白酶,具有严格的底物特异性,能水解多肽链中谷氨酸和(或)天冬氨酸残基的α羧基形成的肽键[1],主要来自于金黄色葡萄球菌V8菌株,故又称为金黄色葡萄球菌V8蛋白酶(Staphylococcus aureusV8 protease)、GluV8或Glu-C
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