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端粒、端粒酶及干细胞

Maternal and Child Health Care of China(2011)

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Abstract
<正>端粒是染色体末端的DNA-蛋白质复合结构,负责维持染色体结构的稳定性和完整性。端粒酶主要由hTERC、hTERT和dyskerin构成,能够合成端粒并维持端粒的长度。端粒的长度和端粒酶活性影响干细胞的老化和肿瘤的形成,端粒的缩
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