microRNA与肿瘤
Sichuan Medical Journal(2011)
Abstract
<正>microRNA(miRNA)是一类长度为18~25个核苷酸的单链非编码RNA,广泛存在于真核生物中,主要通过与靶mRNA的3’端非翻译区(3’UTR)完全或部分互补结合,导致mRNA降解或翻译受到抑制,从而在转录后水平负调控靶基因的表达。虽然自第一个miR-
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