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慢性乙型重型肝炎患者血清sTRAIL的临床价值分析

Journal of Clinical and Experimental Medicine(2010)

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Abstract
目的研究和讨论慢性乙型重型肝炎患者血清中可溶性肿瘤坏死因子相关凋亡诱导配体(sTRAIL)的变化及其临床意义。方法采用双抗体夹心酶联免疫吸附法(ELISA法)对实验组和健康对照组的血清sTRAIL水平进行测定。结果慢性乙型重型肝炎患者血清sTRAIL水平明显高于健康对照组(P<0.01),存活组血清sTRAIL水平明显高于死亡组(P<0.01)。结论 sTRAIL参与了慢性乙型重型肝炎的肝损伤过程,可作为判断预后的重要参数。
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