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MMP-9、TIMP-1及hs-CRP与急性冠状动脉综合征的临床相关性研究

Chinese Journal of Laboratory Diagnosis(2010)

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Abstract
急性冠脉综合征(ACS)包括不稳定心绞痛(UAP)、ST段抬高型和非ST段抬高型心肌梗塞(MI),发病机制为冠状动脉粥样硬化易损斑块破裂及血栓形成,而炎症是导致冠脉易损斑块的形成和不稳定以及闭塞性血栓的重要原因.基质金属蛋白酶(Matrix metalloproteinases.MMPs)降解细胞外基质,是斑块破裂的核心因素.
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