AmpC酶转录调控因子AmpR研究进展

Chinese Journal of Nosocomiology(2010)

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Abstract
AmpC酶,又称头孢菌素酶,Bush分类属于Group-1型,Amber分类属Class C类β-内酰胺酶,能水解三代头孢菌素、头霉素类,不能被酶抑制剂克拉维酸、舒巴坦和他唑巴坦抑制.目前AmpC酶表达的调控机制尚不完全清晰,下面就其调控基因之一ampR的研究现状进行综述.
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