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IgG抗-E致新生儿溶血病换血成功1例

Laboratory Medicine and Clinic(2010)

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Abstract
新生儿溶血病(hemolytic disease of the newborn)是因母婴血型不合,母亲体内存在与胎儿不配合的IgG血型抗体,通过胎盘引起胎儿、新生儿红细胞破坏所致的同族被动免疫性溶血.人类血型系统26个,Rh及ABO血型系统血型不合引起的溶血病最常见.Rh血型不合溶血病主要发生在母亲为Rh阴性、胎儿Rh阳性时,但母亲为Rh阳性时亦可发生,其中抗-E较多见,是由抗-E(母为ee)引起.且RhE抗原仅次于RhD.本例即是由抗-E引起的新生儿溶血病.
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