Aβ单链抗体基因腺相关病毒载体的构建
Acta Academiae Medicinae Sinicae（2009）
Abstract
阿尔茨海默病(Alzheimer's disease, AD)的发生、发展和β淀粉样肽(amyloid β peptide, Aβ)在大脑组织的过载和神经毒性密切相关~([1]).动物实验和临床测试结果均表明Aβ疫苗免疫接种或Aβ抗体的外周注射有助于清除大脑组织内过载的Aβ~([2-3]).
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