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不同剂量氯胺酮对术后PCIA吗啡用量的影响

Chinese Journal of Misdiagnostics(2008)

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Abstract
目的:观察术前单次应用不同剂量氯胺酮对术后吗啡用量的影响。方法:80例下肢手术患者随机分为四组,A组静注氯胺酮0.25 mg/kg、B组0.20 mg/kg、C组0.15 mg/kg、D组0.10 mg/kg。观察术后24 h吗啡用量、镇痛评分及副作用。结果:C组吗啡用量、镇痛评分与A、B组相当,副作用却显著降低。结论:0.15 mg/kg氯胺酮可减少吗啡用量且副作用轻微。
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