β环糊精包合血竭抗PAF诱导血小板聚集作用机理探讨

Pharmacology and Clinics of Chinese Materia Medica(2008)

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Abstract
目的:探讨β环糊精包合血竭的抗血小板聚集作用。方法:Born比浊法测定家兔血小板聚集功能;荧光分光光度法测定血小板细胞钙离子水平。结果:包合血竭体内、外均显著抑制血小板活化因子(PAF)诱导的家兔血小板聚集,同时明显减少兔洗涤血小板内钙释放及外钙内流。结论:包合血竭有抗PAF作用,其机理与影响血小板钙离子水平有关。
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