尿毒症患者外周血T淋巴细胞亚群分析
Chinese Journal of Misdiagnostics(2007)
Abstract
目的:探讨尿毒症患者外周血T淋巴细胞亚群的变化。方法:采用间接免疫荧光法检测35例尿毒症(未透析)患者外周血T淋巴细胞亚群(CD3+、CD4+、CD4+/CD8+)并与30例正常人对照组进行对比。结果:尿毒症组CD3+、CD4+和CD4+/CD8+的比值均显著低于正常对照组(P<0.001)。结论:尿毒症患者存在T淋巴细胞免疫功能紊乱,表现在T淋巴细胞亚群失衡。
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