Cytogenetic Effects of Antibodies to γ-Interferon in Ultralow Doses

O. L. Voronova, O. P. Rogozina,A. V. Martyushev,S. A. Sergeeva,O. I. Epstein,A.M. Dygai,E.D. Goldberg

Bulletin of Experimental Biology and Medicine（2003）

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摘要

Single and course administration of ultralow doses of antibodies γ-interferon did not increase the incidence of cytogenetic abnormalities in bone marrow cells from BALB/c mice and produced no genotoxic effect on Drosophila melanogaster wing cells in the test of somatic mosaicism.

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关键词

ultralow doses,antibodies to human γ-interferon,mutagenicity

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