Multi-centered clinical study on effects of nano-Amomi Paste in treating children’s anorexia
Chinese Journal of Integrative Medicine(2007)
Abstract
Objective To assess the effect and safety of nano-Amoni Paste (nmAP) in the treatment of children’s anorexia (AR). Methods One hundred and eighty patients of AR were assigned according to the randomized, double-blinded, double-simulated and parallel controlled principle to three groups, the treated group (TG), the positive control group (PCG) and the negative control group (NCG), 60 in each group. The patients in TG were treated by sticking 1.5 ml of nmAP on the acupoint of Shenque (Ren 8) once a day and orally taking placebo liquid 10 ml twice a day; those in PCG and NCG treated with sticking paste of placebo on Ren 8, and oral taking of Shanmai Jianpi Oral Liquid (山麦健脾口服液) and placebo liquid respectively, 10 ml each time twice per day. The course of treatment for all was 10 days, all patients were treated for 2 courses. Results The total effective rate and the effective rate on cardinal symptom in TG was 85.0% and 95.0% respectively, that in PCG 86.2% and 96.55% and in NCG 45.5% and 65.45%, respectively, showing significant difference between groups ( P <0.05). Comparison of the clinical manifestation before and after treatment showed significant improvement in volume of food intake, appetite, complexion and reduction of restlessness symptom ( P <0.05) in all three groups, and there was no adverse reaction found in them. Conclusion nmAP is an effective and safe remedy for treatment of Children’s anorexia.
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Key words
nano-liposome,amoni volatile oil,paste
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