AB25-5: Combined spectral mapping guided AF-Nests ablation and pulmonary vein antrum isolation: A new approach to improve AF ablation success

Real time spectral mapping (SM) in sinus rhythm (SR) identifies sites with fibrillar atrial myocardium with high and disorganized frequencies [resonant], namely AF-Nest (AFN). Ablation of AFNs in both atria has been successfully used as an alternative approach to pulmonary vein isolation (PVI) in pts with atrial fibrillation (AF). PVI, at its antrum level (PVAI), combined with isolation of the superior vena cava (SVCI) have decreased post procedure (>2 months) AF recurrences to 17% in paroxysmal (PAF) and 30% in persistent / permanent AF. The potential benefit of AFN ablation added to PVAI was evaluated in this prospective, randomized study.