A Workflow for Computational Fluid Dynamics Simulations using Patient-Specific Aortic Models

Summary Purpose: In this paper, we developed a workflow to simulate the blood flow within patient-specific models of the aorta. The workflow allows Computational Fluid Dynamics (CFD) simulations based on the Finite Volume Methods (FVM) to compute velocity profiles and pressure distributions in the aorta. Methods: The workflow includes the segmentation of patient-specific tomographs and the generation of 3D geometrical models. Then, high-quality meshes required for running and converging the numerical simulations are generated. Realistic boundary conditions are set based on MR flow measurements. Finally, the simulation and analysis of flow patterns and pressure distribution in the aorta is performed using a CFD software (Fluent). Results: We applied the workflow to an abdominal aortic model obtained from a CT scan. Careful processing of all steps was performed in order to generate accurate simulations. The computational results showed mathematically stable solutions characterized by a fast convergence, few numbers of iterations and small residuals. Conclusion: In conclusion, our workflow allows a CFD analysis based on patient-specific data to simulate, describe and analyse the hemodynamics of blood flow within aortic models. It represents a milestone toward an optimal workflow that can be implemented clinically. This may offer a method to aid the diagnosis of aortic aneurysms and their risk of rupture, as well as to plan and control the efficiency of endovascular treatments.