Sepharose-bound, highly sulfated glycosaminoglycans can capture HIV-1 from culture medium.

Barbara Curatella,Barbara Bartolini,Antonino Di Caro,Rosaria A Cavallaro,Lino Liverani,Giuseppe Mascellani,Arrigo Benedetto,Concetta Castilletti,Maria R Capobianchi,Luciano Cellai

Carbohydrate Research（2005）

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摘要

Chemically oversulfated glycosaminoglycans sulfate, bound to Sepharose and packed into columns, removed HIV-1 (IIIB laboratory strain and one clinical isolate) from infected cell culture medium very efficiently.

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关键词

Chondroitin sulfate,Dermatan sulfate,Heparin,Oversulfated glycosaminoglycans,HIV-1

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