Intramolecular guanidine epoxide ring opening reactions

Tetrahedron Letters(2003)

Cited 25|Views15
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Abstract
The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported. A preliminary investigation of the glycosidase inhibitory activity of these substances is also discussed.
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Key words
guanidines,epoxides,iodocyclisations,β-galactosidase inhibition
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