Intramolecular guanidine epoxide ring opening reactions
Tetrahedron Letters(2003)
Abstract
The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported. A preliminary investigation of the glycosidase inhibitory activity of these substances is also discussed.
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Key words
guanidines,epoxides,iodocyclisations,β-galactosidase inhibition
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