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影响原发性肝癌术后行TACE肿瘤复发因素的分析

Chinese Journal of General Surgery(2013)

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Abstract
目的:探讨影响原发性肝癌术后行经肝动脉化疗栓塞(TACE)患者无瘤生存的因素。方法:回顾性分析121例手术切除后1~2个月内行TACE治疗的原发性肝癌患者的临床及随访资料,计算患者治疗后的累积无瘤生存率,分析影响无瘤生存的相关因素。结果:121例患者术后1,2,3年的无瘤生存率分别为72.73%,46.21%,28.93%。经单因素分析筛选后,进入COX比例风险模型的各临床变量中,肿瘤的分化程度(P=0.040),肿瘤大小(P=0.002)及有无血管癌栓(P=0.039)对模型贡献有统计学意义。结论:分化程度、肿瘤的大小及有无血管癌栓是影响肝癌术后行TACE近期复发的独立危险因素。
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Key words
Liver Neoplasms,Statistical,Disease-Free Survival,Hepatectomy,Transarterial Chemoembolization,Factor Analysis
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