851 Field Carcinogenesis Detection By Rectal Spectral Markers Accurately Identifies Patients Harboring Proximal Advanced Adenomas

behavior such as increased anxiety during disimpaction week) were assessed.Primary outcome: successful disimpaction (defined as absence of a fecaloma upon rectal examination or on X-ray, in case patients were too afraid of a second rectal examination).Secondary outcomes were: frequency of fecal incontinence and defecation, presence of watery stools and abdominal pain, behavior questionnaire scores and CTT values.Results Ninety-five patients were eligible; five refused participation.The 90 included patients (60 male) had a mean age of 7.5±2.8years.Forty six were assigned to enemas and 44 to PEG.Five patients dropped out in both groups.Disimpaction was equally achieved with enemas (88%) and PEG (77%); p=0.32.Fecal incontinence (p<0.001) and watery stools (p<0.001) were more frequently reported with PEG (p<0.01) but defecation frequency (p=0.68) and abdominal pain (p=0.23) were not different between the groups.Anxiety (93% vs. 79%; p=0.13) was not different between respectively the enema and the PEG group.Although the enema group (n=39) and the PEG group (n=33) showed decreasing CTT (minus 63 and 66 hours respectively) and RSTT values (minus 31 and 38 hours respectively), between baseline and after six days of disimpaction, no differences between both groups were noted, (after adjustment for baseline values) with regard to CTT and RSTT values after disimpaction (p=0.85 and p=0.06 respectively).Conclusion Rectal enemas and oral laxatives are equally effective in treating rectal fecal impaction.Compared to enemas, oral laxatives caused more fecal incontinence with comparable behavior scores.Both treatments should therefore be equally considered as first line therapy for rectal fecal impaction.