Oversulfated chondroitin sulfate is not the sole contaminant in heparin

NATURE BIOTECHNOLOGY(2010)

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To the Editor: Contaminated heparin was associated with at least 149 deaths in 2007 and 2008, according to the information published at the US Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ PostmarketDrugSafetyInformationforPatientsandProviders/ucm112669.htm). Sasisekharan and his colleagues1, 2, 3 have analyzed 6 lots of heparin associated with the contamination event and 28 lots… Download references
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nature,biotechnology
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