瑞芬太尼与芬太尼对小儿斜视纠正术术后恶心呕吐和疼痛的影响的对比研究
China Practical Medicine(2010)
Abstract
目的对比短时效阿片类药物-瑞芬太尼与芬太尼对小儿斜视术后呕吐和疼痛的作用的差别。方法60名ASAI~II级,2~12岁择期在全麻下行斜视纠正术的小儿,随机分为两组,R组(瑞芬太尼)与F组(芬太尼)。术后记录25 h呕吐事件。苏醒后60 min记录疼痛评分。结果两组术后呕吐发生率没有统计学差异(49%vs 48%)。但是R组术后呕吐频率较F组低(0.95 vs 2.2)。苏醒后头30 min,F组术后疼痛评分较低。结论平衡全麻下小儿斜视术后,瑞芬太尼组术后呕吐发生频率较少,但芬太尼组对术后早期镇痛效果较好。
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Key words
Fentanyl,Remifentanil,Pain,Strabismus surgery,PONV
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