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心脏横纹肌中胱硫醚-γ-裂解酶的表达及意义

ZHANG Tao,ZHANG Hai-tao,LIU Chao-zhong,TAN Cheng,HUANG Cong-chun,WANG Jun-hua

Chinese Journal of Clinical and Experimental Pathology（2012）

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Abstract
目的探讨心脏横纹肌中胱硫醚-γ-裂解酶(cystathionine-γ-lyase,CSE)的表达及意义。方法以SD大鼠心肌为研究对象,采用免疫组化SP法观察心脏横纹肌中CSE的表达,棕褐色为阳性表达。结果心脏横纹肌组织中无CSE阳性表达,心脏血管组织中有CSE阳性表达。结论心脏横纹肌不含有CSE。在心血管系统中起重要调节作用的硫化氢不在心脏横纹肌中代谢生成,主要由外源途径生成。
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Key words
immunohistochemistry,cystathionine-γ-lyase,cardiac striated muscle,hydrogen sulfide
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