331 Tamoxifen may inhibit hepatic fibrogenesis by suppressing the activation of hepatic stellate cells

J.-A. Kim,Y.-H. Chung,M.K. Jang, J.K. Lee,M.H. Choi,S.H. Kim,S.H. Ryu,J.W. Shin,K.M. Kim,Y.S. Lim,Y.S. Lee,D.J. Suh

JOURNAL OF HEPATOLOGY（2006）

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摘要

04C. Molecular and cellular biology (e) HSCs and fibrosis S127Conclusion: Our results show that the invalidation of IGF-1R in hepatocytes attenuates hepatic injury and the fibrogenic response induced by biliary obstruction.

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hepatic stellate cell

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