FIC1, the protein affected in two forms of hereditary cholestasis, is localized in the cholangiocyte and the canalicular membrane of the hepatocyte

Elaine F. Eppens,Saskia W.C. van Mil,J.Marleen L. de Vree,Kam S. Mok,Jenneke A. Juijn,Ronald P.J. Oude Elferink,Ruud Berger,Roderick H.J. Houwen,Leo W.J. Klomp

Journal of Hepatology（2001）

引用 119|浏览9

暂无评分

摘要

Background/Aims: FIC1 (familial intrahepatic cholestasis 1) is affected in two clinically distinct forms of hereditary cholestasis, namely progressive familial intrahepatic cholestasis type 1 (PFIC1) and benign recurrent intrahepatic cholestasis. Here we examined the subcellular localization of this protein within the liver.

查看译文

关键词

FIC1,Intrahepatic cholestasis,Liver,Canalicular membrane,PFIC1,Benign recurrent intrahepatic cholestasis,Hepatobiliary transport,P-type ATPase

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要