同种异体非整块肝脏-小肠联合移植

Hepatobiliary & pancreatic diseases international : HBPD INT(2004)

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Abstract
目的报告国内首例同种异体非整块肝肠联合移植,重点讨论外科技术,并与整块肝肠联合移植技术进行比较.方法患者因短肠综合征和全肠外营养(TPN)肝病接受非整块肝肠联合移植,植入小肠380 cm.肠系膜上动脉、门静脉分别与受体腹主动脉、下腔静脉端侧吻合;供肝行改良背驮式肝移植.供体热缺血时间为2 min 30 s,移植肠冷缺血6 h 40 min,移植肝冷缺血8 h 7 min.术后免疫抑制方案采用FK506+激素+骁悉+赛尼哌.结果患者恢复顺利,未发生排斥反应,至今仍存活,已恢复完全肠道营养.结论非整块肝肠联合移植技术适合于成年受体,特别是既往曾有腹腔感染或接受多次腹部手术的患者.
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Key words
liver transplantation,intestinal transplantation,combined liver and intestinal transplantation,transplantation,total parenteral nutrition
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