Clinical Laboratory Analysis of the Genetically Manipulated Mouse

The importance of analyzing routine chemistries in living genetically manipulated mice is increasingly clear. Analogous data bases of serum and/or plasma analytes exist for humans, are commonly used in screening human patients for the presence of health and disease, and serve as important clinical screening tools for the presence of cardiovascular diseases, their prognosis, and efficacy of therapy. These data are absent or incomplete for the mouse. In a correlative way, the availability of these data will amplify the ability scientists to screen for cardiovascular and other diseases in the genetically manipulated mouse.