Chron's disease, rare association with selective IgA immunodeficiency, and development of life-threatening bacterial infections.
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES(2009)
Abstract
Life-threatening necrotizing fasciitis and relapsing Lemierre syndrome associated with Fusobacterium necrophorum septicaemia occurred in young adults with a moderate Chron's disease and a missed profound IgA deficiency. This unexpected association of a chronic bowel inflammatory syndrome with prominent IgA abnormalities and severe bacterial infection deserves careful attention by physicians faced with young patients with Chron's disease.
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Key words
selective iga immunodeficiency,chron,bacterial infections,disease,life-threatening
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