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AFU、TC在恶性腹水和非结核良性腹水鉴别诊断中的价值

Jiangsu Medical Journal(2010)

Cited 23|Views8
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Abstract
目的 探讨α-L-岩藻糖苷酶(AFU)和总胆固醇(TC)在恶性腹水和非结核性良性腹水鉴别诊断价值.方法 应用半自动生化分析仪对221例腹水进行AFU活性和TC测定.结果 恶性腹水AFU和TC为(173.895±92.40)μmol·L~(-1)·h~(-1)和(1.69±0.98)mmol/L,明显高于非结核性良性腹水的(103.07±57.11)μmol·L~(-1)·h~(-1)和(0.70±0.60)mmol/L(P<0.01).以AFU120μmol·L~(-1)·h~(-1)和TC 1.1 mmol/L为界值,恶性腹水的敏感性分别为67.65%和75.63%,特异性分别为72.55%和85.71%;两项联合检测的敏感性、特异性为77.45%、91.59%.结论 腹水AFU、TC的活性测定有助于恶性腹水和非结核性良性腹水鉴别诊断;两者联合检测可提高鉴别诊断的敏感性和特异性.
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Key words
Total cholesterol,Differential diagnosis,Ascites,α-L-fucosidase
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