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PANcreatic-DERived factor: Novel hormone PANDERing to glucose regulation

Camella G. Wilson,Claudia E. Robert-Cooperman,Brant R. Burkhardt

FEBS Letters（2011）

Cited 26|Views8
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Abstract
► PANDER serves as a novel hormone regulating glycemic levels. ► PANDER is positively regulated by glucose and insulin. ► PANDER impacts pancreatic β-cell glucose-stimulated insulin secretion. ► PANDER interacts with liver and increases hepatic glucose production. ► High fat animal models demonstrate increased PANDER expression and hepatic action.
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Key words
PANDER,FAM3B,Glucose regulation,Islets
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