Increased thrombin generation measured in the presence of thrombomodulin in women with early pregnancy loss
Fertility and Sterility(2011)
摘要
Compared with 537 parous controls with no history of pregnancy loss, a lower thrombomodulin-related inhibition of the endogenous thrombin potential was measured in 264 cases with previous unexplained pregnancy loss, especially when losses occurred between 9 and 12 weeks of gestation. Adjusting age, protein S, factor VIII, factor V Leiden, and prothrombin G20210A did not change the results.
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关键词
Case-control study,thrombin generation test with and without thrombomodulin,pregnancy loss,protein S,factor VIII
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