Molecular Engineering of a Cryptic Epitope in Spike RBD Improves Manufacturability and Neutralizing Breadth Against SARS-CoV-2 Variants
Sergio A. Rodriguez-Aponte,Neil C. Dalvie,Ting Y. Wong,Ryan S. Johnston,Christopher A. Naranjo,Sakshi Bajoria,Ozan S. Kumru, Kawaljit Kaurg,Brynnan P. Russ,Katherine S. Lee,Holly A. Cyphert,Mariette Barbier,Harish D. Rao,Meghraj P. Rajurkar,Rakesh R. Lothe,Umesh S. Shaligram,Saurabh Batwal,Rahul Chandrasekaran,Gaurav Nagar,Harry Kleanthous, Sumi Biswasj,Justin R. Bevere,Sangeeta B. Joshi, David B. Volking,F. Heath Damron,J. Christopher Love International Psychogeriatrics（2001）
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SARS-CoV-2 RBD,Variants of concern,Vaccine manufacturing,Protein engineering,Pichia pastoris,Komagataella phaffii,Comirnaty
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