Inhibition of NF-kappa B augments sensitivity to 5-fluorouracil/folinic acid in colon cancer.
The Journal of surgical research（2004）
Abstract
Treatment with 5-FU activates NF-kappaB. Folinic acid enhances 5-FU-mediated activation of NF-kappaB. Inhibition of NF-kappaB enhances the cytotoxic effect of 5-FU with or without Folinic acid in colon cancer cells.
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Key words
5-fluorouracil/folinic acid,nf-kappa
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