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Postoperative radiotherapy for laryngeal cancer. The prognostic role of programmed death-ligand 1: An immune microenvironment-based cluster analysis.

Leonardo Franz,Lara Alessandrini,Giancarlo Ottaviano,Roberto di Carlo,Elena Fasanaro,Giulia Ramacciotti,Giacomo Contro,Gino Marioni

Pathology - Research and Practice（2020）

Cited 13|Views21
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Abstract
Judging from this preliminary investigation, assessing PD-L1 and immune microenvironment markers seems a promising approach for identifying patients at higher risk of LSCC recurrence after PORT, who might reasonably benefit from adjuvant postoperative chemo-RT, or immunotherapy.
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Key words
Laryngeal squamous cell carcinoma,Postoperative radiotherapy,Programmed death-ligand 1,Tumor-infiltrating lymphocytes, tertiary lymphoid structures,Prognosis
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