Deficits in auditory P50 inhibition in obsessive-compulsive disorder.

Tasuku Hashimoto,Eiji Shimizu,Kaori Koike,Yasuhiro Orita,Tomotaka Suzuki,Nobuhisa Kanahara,Daisuke Matsuzawa,Goro Fukami,Ryosuke Miyatake,Naoyuki Shinoda,Mihisa Fujisaki,Yukihiko Shirayama,Kenji Hashimoto,Masaomi Iyo

Progress in Neuro-Psychopharmacology and Biological Psychiatry（2008）

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摘要

Obsessive–compulsive disorder (OCD) is considered to involve abnormalities in inhibitory processes including gating systems. Auditory P50 inhibition, which is assessed by using a paired auditory stimulus paradigm to record P50 mid-latency evoked potential, is assumed to reflect sensory gating.

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关键词

BDI,EEG,EOG,GAF,OCD,PPI,PTSD,SDMT,SEP,SRI,T/C,TMT,Y-BOCS

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