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经阴道超声评估来曲唑对多囊卵巢综合征的治疗作用

Reproduction & Contraception(2007)

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Abstract
目的:通过阴道超声评估来曲唑对多囊卵巢综合征(PCOS)的治疗作用。方法:来曲唑治疗38例PCOS患者,经阴道超声观察宫颈前后径、子宫内膜厚度和形态、优势卵泡个数,子宫动脉和卵巢基质血流PSV、EDV、PI、RI,与超声观察同天测定血清FSH、LH、E2、P,并与52例正常育龄妇女相比较。结果:来曲唑治疗PCOS有较高的排卵率(81.58%)和妊娠率(21.05%),并使子宫卵巢出现类似正常育龄妇女的周期性血流变化。结论:来曲唑改善了PCOS患者的子宫卵巢血流供应,利于妊娠。
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Key words
polycystic ovary syndrome(PCOS),Letrozole,the blood flow of uterus and ovary,color Doppler ultrasound
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