16S rRNA methylase-producing, gram-negative pathogens, Japan.

Kunikazu Yamane,Jun-ichi Wachino,Satowa Suzuki,Naohiro Shibata,Haru Kato,Keigo Shibayama,Kouji Kimura,Kumiko Kai,Satoshi Ishikawa,Yoshiyuki Ozawa,Toshifumi Konda,Yoshichika Arakawa

EMERGING INFECTIOUS DISEASES（2007）

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摘要

To investigate the exact isolation frequency of 16S rRNA methylase-producing, gram-negative pathogenic bacteria, we tested 87,626 clinical isolates from 169 hospitals. Twenty-six strains from 16 hospitals harbored 16S rRNA methylase genes, which suggests sparse but diffuse spread of pan-aminoglycoside-resistant microbes in Japan.

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methyltransferases

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