Establishment of Biofilm Model in Vitro of Clinical C.jejuni isolation and Studies of its Influence Factors

C.jejuni is a worldwide prevalent pathogen of zoonotic disease,was very hypercritical to the living conditions.In recent years,some scholars had found that,the bacteria could form a biofilm to resist the adverse external environmental impact under certain conditions,this was also the important reason for the bacteria to survive harsh environment and drug resistance.We chose Campylobacter jejuni isolated from clinical samples as the research object in this study,built the biofilm model in vitro,established by a series of methods,such as PCR,scanning electron microscope and the orthogonal experiment,to study the characteristics and influence factors of the bioflm,looking forward to getting some useful results for clinical prevention and treatment and elimination of the drug resistance.