Drug retention in the coronary and femoral arteries is dependent on the route of administration in swine: assessment of intimal and adventitial endovascular and systemic pharmacokinetics and toxicology with nanoparticle albumin-bound paclitaxel

Cardiovascular Revascularization Medicine(2010)

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Abstract
Gold nanoparticles (AuNPs) are a suitable platform for development of efficient delivery systems. AuNPs can be easily synthesized, functionalized, and are biocompatible. The tunability of the AuNP monolayer allows for complete control of surface properties for targeting and stability/release using these nanocarriers. This review will discuss several delivery strategies utilizing AuNPs.
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Key words
drug retention,paclitaxel,systemic pharmacokinetics,femoral arteries,albumin-bound
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