Determination off the Potencies of the R-(+) and S-(−) Enantiomers off HA-966 As Antagonists of the Glycine Site on the NMDA Receptor Complex
European journal of pharmacology(1990)
摘要
The addition of 2-lithiothiazole to nitrones derived from d-glyceraldehyde and d-arabinose affords anti-adducts from which α-amino aldehydes are revealed by thiazole-to-formyl deblocking. The methodology provides a new synthesis of N-acetyl d-mannosamine and d-mannosamine hydrochloride.
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