Pyrazole derivatives as new potent and selective 20-hydroxy-5,8,11,14-eicosatetraenoic acid synthase inhibitors.

Bioorganic & Medicinal Chemistry(2004)

Cited 69|Views8
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Abstract
Introduction of a piperazino group to the selective and potent 20-HETE synthase inhibitor 1 to obtain potential therapeutic agents with suitable water-solubility for injectable formulation is described.
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Key words
20-HETE,Pyrazole
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