经皮冠状动脉介入对心脏自主神经的影响
Journal of Clinical Cardiology(2008)
Abstract
目的:探讨经皮冠状动脉介入治疗(PCI)后心脏心率变异性(HRV)及QT离散度(QTd)的长期动态变化规律。方法:冠心病组32例,选择经冠状动脉造影证实并适合PCI的冠心病患者;对照组32例,选年龄性别匹配的经皮冠状动脉造影证实的非冠心病患者。所有入选者于PCI前,术后1周、1个月、3个月、6个月及1年进行HRV及QTd检测。结果:冠心病组HRV减低,PCI后1周HRV较术前减低更为明显,术后1,3个月HRV逐步升高,于6个月较术前改善最为明显,术后1年几乎达对照组水平;PCI前QTd较对照组明显增大,术后1周较术前缩小,1个月后明显缩小,以后变化不明显。结论:冠心病患者QTd增大,HRV减低,心脏自主神经功能受损。PCI后QTd短期内明显缩小,心脏自主神经功能PCI后早期进一步受损,但远期明显改善。
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Key words
Coronary disease,Autonomic nerve system,Heart rate variability,Percutaneous coronary intervention
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