Single and Repeated Dose Pharmacokinetics of Thio-Tepa in Patients Treated for Ovarian Carcinoma
Cancer chemotherapy and pharmacology(1987)
Abstract
Triethylenethiophosphoramide (thio-TEPA) pharmacokinetics were studied in 15 patients being treated for epithelial ovarian carcinoma. Unchanged thio-TEPA was assayed in serum and urine by means of a gas chromatographic procedure.
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Key words
Ovarian Carcinoma,Renal Clearance,Drug Monitoring,Apparent Volume,Repeated Dose
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