613 Cytokine response in chronic hepatitis C (CHC) patients treated with pegylated interferon plus ribavirin

05G. Viral Hepatitis (g) Hepatitis C Clinical therapy$227 losartan administration.A significant increase was observed in albumin level and platelet counts in the treated patients.Acute (3 h) and chronic (one month) decreases in systolic arterial pressures in supine position were observed after losartan administration.Nevertheless, only one patient referred a single episode of mild orthostatic hypotension.No differences were observed in renal function tests.Conclusion: chronic AT1R blockade may reduce liver fibrosis in chronic hepatitis C patients.